Implen NanoPhotometer®: The Gold Standard in Microvolume Spectroscopy
Discover the unparalleled accuracy, flexibility, and reliability of the NanoPhotometer® family, engineered in Germany for today’s demanding life science workflows.
In This Guide, You’ll Learn:
- The core technologies, Sample Compression™ and True Path™, that guarantee lifetime accuracy without recalibration.
- How the different NanoPhotometer® models (N120, NP80, N60, N50, C40) compare to help you select the right instrument.
- The advanced workflow, connectivity, and compliance features that streamline laboratory operations.
Estimated Read Time: 5 minutes
Precision Engineered for Modern Science
Since 2003, Implen has established itself as a global leader in spectroscopy, delivering innovative instruments for the non-destructive analysis of ultra-low volume liquid samples. The NanoPhotometer® series, proudly engineered and manufactured in Germany, represents the pinnacle of microvolume UV/Vis spectrophotometry, trusted by the world’s most prestigious biological, chemical, and pharmaceutical research organizations.
Unmatched Performance
Offering best-in-class products that support critical workflows, the NanoPhotometer® line is cited in thousands of scientific publications, a testament to its reliability and proven results.
Quality First. Always.
With an ISO 9001:2015 certified Quality Management System, every instrument is fully tested to exceed expectations for functionality, robustness, and longevity.
Innovative Design
Compact, intuitive, and powerful, our products are designed with the user in mind, providing a degree of flexibility and data connectivity never before seen in laboratory spectroscopy.
Service & Calibration-Free
Thanks to patented True Path Technology™, all NanoPhotometer® instruments guarantee lifetime accuracy, eliminating the need for costly and time-consuming recalibrations or service.
The Technology Behind Lifetime Accuracy
The NanoPhotometer’s industry-leading performance is built on a foundation of patented core technologies that eliminate common sources of error found in other microvolume instruments. This ensures you get accurate, reproducible data, every single time.
Sample Compression Technology™
Unlike instruments that rely on surface tension, the NanoPhotometer® uses its proprietary Sample Compression Technology™. This system forms a precisely defined capillary film by enclosing the sample between two quartz surfaces, much like a microscope slide and coverslip.
- Eliminates Evaporation: The enclosed sample environment minimizes solvent evaporation, which is critical for volatile organic solvents and for maintaining concentration during longer measurements.
- No Surface Tension Required: Delivers accurate readings even for challenging protein samples and detergent-based buffers that fail on other systems.
- Unmatched Linearity: Works with two precisely defined, fixed path lengths to guarantee linearity across the instrument’s entire detection range.
True Path Technology™
Implen guarantees lifetime accuracy with its maintenance-free True Path Technology™. This sealed, robust mechanical setup ensures the path lengths never change, eliminating drift and the need for recalibration.
- Recalibration-Free: Two fixed anchor points define the path lengths. Since these points are immobile, the path length cannot drift, saving you costly and time-consuming service calls.
- Durable & Inert: The unique quartz-based, metal-free measurement surfaces are scratch-resistant and chemically inert, allowing for a wide range of solvents and buffers.
- Guaranteed Precision: The path length is set by a magnet that can only position the pedestal at one of the two fixed anchor points, ensuring absolute precision with every measurement.
Find Your Perfect Fit: The NanoPhotometer® Family
Whether you need the high-throughput screening of the N120, the flexible all-in-one capability of the NP80, a dedicated nanovolume solution like the N60 or N50, or a cuvette-based system like the C40, there is a NanoPhotometer® model designed for your lab.
| Feature | N120 | NP80 | N60 | N50 | C40 |
|---|---|---|---|---|---|
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| Primary Application | 12-Channel NanoVolume | NanoVolume & Cuvette | NanoVolume | NanoVolume | Cuvette |
| Sample Throughput | 1-12 Samples | 1 Sample | 1 Sample | 1 Sample | 1 Sample |
| Minimum Sample Volume | 2 µL | 0.3 µL | 0.3 µL | 0.3 µL | Cuvette Dependent |
| Full Spectrum Scan | 200 – 900 nm | 200 – 900 nm | 200 – 900 nm | 200 – 650 nm | 200 – 900 nm |
| dsDNA Detection Range (Nano) | Up to 8,000 ng/µL | Up to 16,500 ng/µL | Up to 16,500 ng/µL | Up to 7,500 ng/µL | N/A (Upgradeable) |
| BSA Detection Range (Nano) | Up to 230 mg/mL | Up to 478 mg/mL | Up to 478 mg/mL | Up to 217 mg/mL | N/A (Upgradeable) |
| dsDNA Detection Range (Cuvette) | N/A | 0.1 – 130 ng/µL | N/A | N/A | 0.1 – 130 ng/µL |
| Built-in Cuvette Port | No | Yes | No | No | Yes |
| Built-in Vortex | No | Yes | Yes | No | No |
| Built-in Battery Pack | Optional | Optional | Optional | No | Optional |
| 21 CFR Part 11 Software | Optional | Optional | Optional | No | Optional |
| IQ/OQ Package | Optional | Optional | Optional | No | Optional |
Intelligent Design for a Seamless Workflow
Every NanoPhotometer® is packed with features designed to save you time, eliminate errors, and provide ultimate flexibility in how you work.
Flexible Unit Control
Operate your instrument from its glove-compatible touchscreen, or control it remotely from any PC, Mac, smartphone, or tablet. The NPOS operating system provides a consistent, intuitive experience on any device.
Endless Connectivity
Equipped with WiFi, LAN, USB, and HDMI, data access is effortless. Connect to network printers, save data to the built-in file server, or export results directly to a USB drive. The built-in HotSpot allows direct connection from mobile devices.
Certainty in Real Time
Sample Control™ actively monitors for impurities, turbidity, and air bubbles, while Blank Control™ flags high-background blanks, protecting you from wasting precious samples and time on inaccurate readings.
Stand-Alone Powerhouse
With an integrated computer and 32 GB of onboard storage (128 GB for the N120), no external PC is required. The optional battery pack provides up to 8 hours of operation, making it truly mobile for use in clean benches or in the field.
Universal Printing & Barcodes
Print full reports or labels directly to AirPrint, HP Universal, and DYMO label printers. Streamline sample entry by connecting a compatible 1D/2D barcode reader to automatically import sample names.
Fast and Efficient
A Xenon flash lamp means no warm-up time is needed—power on and measure instantly. Full spectrum scans are completed in as little as 1.7 seconds per sample, dramatically accelerating your workflow.
Ready for Regulated Environments
For GxP laboratories that demand data integrity and regulatory compliance, the NanoPhotometer® offers optional software and qualification packages that provide uncompromised security and a complete audit trail.
21 CFR Part 11 Compliance
The optional CFR21 software provides password-protected user accounts with role-based access, electronic signatures, secure data integrity, and a comprehensive audit trail to meet FDA requirements.
Seamless LIMS Integration
Utilize the NanoPhotometer® REST API to fully integrate the instrument into your LIMS. Execute methods, retrieve data, and auto-populate results without error-prone manual data entry.
IQ/OQ Documentation
Our IQ/OQ package provides documented verification that your instrument is functioning to specification. It includes NIST traceable standards and an Excel-based tool to generate automated reports for audits.
Ready to Elevate Your Spectroscopy Workflow?
Experience the German-engineered precision and unparalleled flexibility of the Implen NanoPhotometer®. Contact our specialists today to schedule a demo or request a quote.