Urine Preservative Single Dose – 18124

Urine Preservative Single Dose: Long-Term Ambient Stabilisation of Nucleic Acids and Proteins

Norgen’s Urine Preservative is a high-performance aqueous solution engineered for the rapid stabilisation of DNA, RNA, microRNA and proteins within fresh urine samples. It addresses the critical challenge of sample degradation during transport and storage by eliminating the immediate requirement for refrigeration or freezing. By providing a professional-grade solution for clinical and research laboratories, this preservative allows for decentralised sample collection while maintaining high-quality molecular signatures for over two years at room temperature.

The technology functions by creating a protective chemical environment that inhibits the growth of both Gram-negative and Gram-positive bacteria as well as fungi, preventing metabolic shifts that could alter the sample profile. Simultaneously, the preservative inactivates viruses, rendering potentially infectious urine samples non-infectious for safer handling and shipping under ambient conditions. Crucially, the buffer preserves exfoliated cells, bacterial cells, and viruses without inducing lysis, ensuring that downstream analysis accurately reflects the biological state of the sample at the time of collection.

Key Benefits:

• Ambient Stability: Extended preservation for over two years. Nucleic acids and proteins remain stable at room temperature, facilitating long-term storage and cost-effective shipping without the need for dry ice.
• Enhanced Biosafety: Viral inactivation for safer handling. The preservative effectively inactivates viruses, reducing biohazard risks and allowing samples to be transported with greater safety for laboratory personnel.
• Microbial Control: Prevention of bacterial and fungal growth. Inhibits the proliferation of contaminating microorganisms to ensure the molecular integrity of the urine sample is maintained throughout the workflow.
• Streamlined Workflow: Elimination of immediate processing. Removes the requirement for onsite centrifugation or freezing, allowing samples to be collected and sent directly to centralised testing facilities.
• Universal Compatibility: Optimised isolation performance. Samples preserved in this solution are compatible with most major DNA, RNA and protein isolation methods, including Norgen’s comprehensive range of purification kits.

Technical Insights

The preservation process is designed for simplicity and reliability in both clinical and field settings. Once a fresh urine sample (typically 5 mL to 50 mL) is collected into a standard sterile container, the tip of the single-dose liquid ampule is removed and the entire contents are dispensed into the urine. Upon gentle inversion, the preservative is homogenised with the sample, initiating immediate stabilisation. This format is ideal for integration into high-throughput collection programmes where immediate access to laboratory infrastructure is limited.

Specifications

• Format: Liquid Single Dose Ampule
• Urine Input Volume: 5 mL – 50 mL
• Stability: > 2 Years at Room Temperature (15–25°C)
• Analytes Preserved: DNA, RNA, microRNA, Proteins
• Sample Type: Fresh Urine (Human, Animal)